scAAVIL-1ra dosing trial in a large animal model and validation of long-term expression with repeat administration for osteoarthritis therapy

OARSI guidelines for the non-surgical management of knee osteoarthritis

T.E. McAlindon, Raveendhara R. Bannuru, Matthew C. Sullivan et al. · Osteoarthritis and Cartilage · 2014 · 3.1K citations · Full text

Medicine, Orthopaedic Surgery, Physical Medicine +16

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

Virginia Pascual, Florence Allantaz, Edsel Arce et al. · The Journal of Experimental Medicine · 2005 · 917 citations · Full text

Life Sciences, Immunology, Pathobiology +17

Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist.

William P. Arend, Howard G. Welgus, Reid C. Thompson et al. · Journal of Clinical Investigation · 1990 · 592 citations · Full text

Life Sciences, Cell Biology, Immunology +9

Synovial membrane inflammation and cytokine production in patients with early osteoarthritis.

Malcolm Smith, S Triantafillou, Angela Parker et al. · PubMed · 1997 · 529 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman Primates

Steven J. Gray, Valérie Matagne, Lavanya Bachaboina et al. · Molecular Therapy · 2011 · 504 citations · Full text

Pharmacy, Neurobiology, Neuroscience +17