Interspecies scaling of renally secreted drugs

Applied Biopharmaceutics and Pharmacokinetics.

Annals of Internal Medicine · 1981 · 1.2K citations

Medicinal Chemistry, Pharmacokinetics Introduction, Pharmacokinetic Modeling +14

Interspecies Scaling: Predicting Pharmacokinetic Parameters of Antiepileptic Drugs in Humans from Animals with Special Emphasis on Clearance

Iftekhar Mahmood, John Dikran Balian · Journal of Pharmaceutical Sciences · 1996 · 106 citations

Scaling of antipyrine intrinsic clearance of unbound drug in 15 mammalian species

Harold Boxenbaum, Joanne B. Fertig · European Journal of Drug Metabolism and Pharmacokinetics · 1984 · 86 citations

Pharmacological Study, Biochemistry, Mammalian Species +7

Pharmacokinetics, renal clearance and metabolism of ciprofloxacin following intravenous and oral administration to calves and pigs

J. F. M. Nouws, Dik Mevius, T. B. Vree et al. · Veterinary Quarterly · 1988 · 64 citations · Full text

Dose ranging study and constant infusion evaluation of ciprofloxacin

George L. Drusano, Karen I. Plaisance, Alan Forrest et al. · Antimicrobial Agents and Chemotherapy · 1986 · 59 citations · Full text

Preclinical Drug Evaluation, Serum Clearance, Medicine +13