Endogenous levels of Rad51 and Brca2 are required for homologous recombination and regulated by homeostatic re-balancing

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

Peter J. Southern, Paul Berg · PubMed · 1982 · 2.8K citations

Engineering, Molecular Biology, Bacterial Gene +20

Simple and highly efficient BAC recombineering using galK selection

Søren Warming · Nucleic Acids Research · 2005 · 1.2K citations · Full text

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

Eiichiro Sonoda · The EMBO Journal · 1998 · 794 citations · Full text

Chromatin, Genome Instability, Dna Damage +8

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

Teruhisa Tsuzuki, Youichi Fujii, Kunihiko Sakumi et al. · Proceedings of the National Academy of Sciences · 1996 · 790 citations · Full text

Embryonic Mice, Rad51 Null Mutation, Gene Therapies +13

Role of BRCA2 in Control of the RAD51 Recombination and DNA Repair Protein

Adelina A. Davies, Jean‐Yves Masson, Michael J. McIlwraith et al. · Molecular Cell · 2001 · 706 citations · Full text

Chromatin, Genome Instability, Genetics +9