Expression of receptor tyrosine kinases epidermal growth factor receptor and HER‐2/<i>neu</i> in synovial sarcoma

Dafydd G. Thomas, Thomas J. Giordano, Donita Sanders, Sybil J. Biermann, Vernon K. Sondak, Jonathan C. Trent, Dihua Yu, Raphael E. Pollock, Laurence Baker

Cancer · 2005 · 82 citations · 50 references

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Abstract

EGFR and HER-2/neu are expressed in the majority of patients with SYT/SSX1 synovial sarcomas, albeit at low levels. Treatment with tyrosine kinase inhibitors may represent appropriate alternate therapy for these patients.

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