A rice-based soluble form of a murine TNF-specific llama variable domain of heavy-chain antibody suppresses collagen-induced arthritis in mice

Naturally occurring antibodies devoid of light chains

C. Hamers‐Casterman, T. Atarhouch, Serge Muyldermans et al. · Nature · 1993 · 3.2K citations

Pharmacy, Biochemistry, Immunology +14

A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes

Terje Espevik · Journal of Immunological Methods · 1986 · 1.3K citations

Life Sciences, Cell Biology, Immunology +7

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)

Hendrik M. van Dullemen, Sander J. H. van Deventer, Daan W. Hommes et al. · Gastroenterology · 1995 · 1.1K citations

Pharmacy, Immunology, Immunotherapy +9

Selection and identification of single domain antibody fragments from camel heavy‐chain antibodies

Mehdi Arbabi Ghahroudi, Aline Desmyter, L. Wyns et al. · FEBS Letters · 1997 · 766 citations · Full text

Pharmacy, Biotechnology, Immunology +17

Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination

Tomonori Nochi, Hidenori Takagi, Yoshikazu Yuki et al. · Proceedings of the National Academy of Sciences · 2007 · 334 citations · Full text

Life Sciences, Agricultural Biotechnology, Biotechnology +17