Long-Term Use of Probiotics<i>Lactobacillus</i>and<i>Bifidobacterium</i>Has a Prophylactic Effect on the Occurrence and Severity of Pouchitis: A Randomized Prospective Study

Abstract

Nine months of the probiotic treatment (Lactobacillus acidophilus, Lactobacillus delbrueckii subsp. bulgaricus, and Bifidobacterium bifidus) reduced the number of patients with pouchitis, decreased the PDAI score, and also decreased the fecal pyruvate kinase and calprotectin. The long-term probiotics use is safe and well accepted and can be an effective method of the pouchitis prevention.