HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer - Concepedia

Concepedia

Publication | Open Access

HDM2 Regulation by AURKA Promotes Cell Survival in Gastric Cancer

DOI Full Paper Access

65

Citations

35

References

2013

Year

Vikas Sehdev, Ahmed Katsha, Janet Arras, Dunfa Peng, Mohammed Soutto, Jeffrey Ecsedy, Alexander Zaika, Abbes Belkhiri, Wael El‐Rifai

Clinical Cancer Research

Abstract

Collectively, our novel findings indicate that AURKA promotes tumor growth and cell survival through regulation of HDM2-induced ubiquitination and inhibition of P53. Clin Cancer Res; 20(1); 76-86. ©2013 AACR.

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