Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.2K citations · Full text

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A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

Jeffery D. Molkentin, Jianrong Lu, Christopher L. Antos et al. · Cell · 1998 · 2.6K citations · Full text

Cardiac Muscle, Transcriptional Regulation, Cardiomyopathy +8

Mitochondrial control of nuclear apoptosis.

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Mitophagy, Apoptosis, Mitochondrial Permeability Transition +16

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

Jason E. Kokoszka, Katrina G. Waymire, Shawn Levy et al. · Nature · 2004 · 1.1K citations · Full text

Mitochondrial Function, Biochemistry, Natural Sciences +9

The Ca2+-induced membrane transition in mitochondria

Douglas R. Hunter, Robert A. Haworth · Archives of Biochemistry and Biophysics · 1979 · 846 citations

Ca2+-induced Membrane Transition, Mitochondrial Function, Organelle Dynamic +3