Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

Natural Sciences, Rna Splicing, Rna Biology +9

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

Qui‐Lim Choo, George Kuo, Amy J. Weiner et al. · Science · 1989 · 6.9K citations

Vaccination, Viral Replication, Nanbh Agent +15

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma.

Izumu Saito, Tatsuo Miyamura, Akira Ohbayashi et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations · Full text

Immunology, Pathology, Cirrhosis +16

siRNA-directed inhibition of HIV-1 infection

Carl D. Novina, Michael F. Murray, Derek M. Dykxhoorn et al. · Nature Medicine · 2002 · 775 citations

Medicine, Human Retrovirus, Immunology +6

Modulation of HIV-1 replication by RNA interference

Jean-Marc Jacqué, Karine Triques, Mario Stevenson · Nature · 2002 · 716 citations · Full text

Viral Replication, Natural Sciences, Human Retrovirus +6