Toxicity and biodistribution of para-sulfonato-calix[4]arene in mice

Anthony W. Coleman, Saïd Jebors, Sébastien Cecillon, Pascale Perret, Dominique Garin, Danièle Marti‐Battle

New Journal of Chemistry · 2008 · 156 citations · 19 references

Concepts

Abstract

The acute in vivo toxicity of para-35S-sulfonato-calix[4]arene has been determined, with no toxicity for doses up to 100 mg kg−1. Biodistribution shows that the molecule is rapidly cleared in urine, that it does not accumulate in the liver and spleen, and is not observed in the brain.

References

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