The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 <i>via</i> Nuclear Factor Erythroid-2-Related Factor 2 - Concepedia

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The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 <i>via</i> Nuclear Factor Erythroid-2-Related Factor 2

DOI Full Paper Access

189

Citations

55

References

2013

Year

Esther Parada, Javier Egea, Izaskun Buendía, Pilar Negredo, Ana C. Cunha, Sílvia Cardoso, Miguel P. Soares, Manuela G. López

Antioxidants and Redox Signaling

Abstract

Activation of the α7 nAChR/Nrf2/HO-1 axis in microglia regulates neuroinflammation and oxidative stress, affording neuroprotection under brain ischemic conditions.

References

	Year	Citations

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