A Model for a Network of Phosphorylation–dephosphorylation Cycles Displaying the Dynamics of Dominoes and Clocks

A synthetic oscillatory network of transcriptional regulators

Michael B. Elowitz, Stanislas Leibler · Nature · 2000 · 4.8K citations

Life Sciences, Genetics, Molecular Biology +14

An amplified sensitivity arising from covalent modification in biological systems.

Albert Goldbeter, Daniel E. Koshland · Proceedings of the National Academy of Sciences · 1981 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +15

Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation.

Albert Goldbeter, Geneviève Dupont, Michael J. Berridge · Proceedings of the National Academy of Sciences · 1990 · 644 citations

Life Sciences, Biophysics, Cell Biology +17

<i>Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour</i>

Albert Goldbeter, Joel Keizer · Physics Today · 1998 · 625 citations

Natural Sciences, Biochemistry, Biophysics +12

Kinetic Analysis of a Molecular Model of the Budding Yeast Cell Cycle

Katherine Chen, Attila Csikász‐Nagy, Béla Györffy et al. · Molecular Biology of the Cell · 2000 · 479 citations

Life Sciences, Biochemistry, Molecular Biology +17