Antibody Persistence 3 Years after Immunization of Adolescents with Quadrivalent Meningococcal Conjugate Vaccine

Abstract

Compared with MPSV-4, MCV-4 elicited greater persistence of antibody activity against serogroups C and W-135 at 3 years after vaccination in adolescents. On the basis of passive protection data in an infant rat model, bactericidal titers > or =1 : 4 underestimate protective immunity.