Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-κB in AML carrying NPM1 mutations

Fusion of a Kinase Gene, <i>ALK</i> , to a Nucleolar Protein Gene, <i>NPM</i> , in Non-Hodgkin's Lymphoma

Stephan W. Morris, Mark N. Kirstein, Marcus B. Valentine et al. · Science · 1994 · 2.4K citations

Medicine, Genetics, Oncology +17

Cytoplasmic Nucleophosmin in Acute Myelogenous Leukemia with a Normal Karyotype

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Life Sciences, Molecular Biology, Molecular Genetics +14

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

Julian Adams, Vito J. Palombella, Edward A. Sausville et al. · PubMed · 1999 · 1.5K citations

Medicine, Oncology, Pharmacology +14

Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations

Konstanze Döhner, Richard F. Schlenk, Marianne Habdank et al. · Blood · 2005 · 845 citations · Full text

Life Sciences, Genetics, Oncology +11

Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells

Mónica L. Guzmán, Sarah J. Neering, Donna Upchurch et al. · Blood · 2001 · 757 citations

Medicine, Cell Biology, Oncology +7