Concepedia

<i>Porphyromonas gingivalis</i> lipopolysaccharide induces tumor necrosis factor‐α and interleukin‐6 secretion, and CCL25 gene expression, in mouse primary gingival cell lines: interleukin‐6‐driven activation of CCL2

Sanaz Ekhlassi, L. Y. Scruggs, Tomas Garza, Dina Montufar‐Solis, Antonio J. Moretti, John R. Klein

Journal of Periodontal Research · 2008 · 30 citations · 30 references

DOI

Abstract

These findings define a pathway in which exposure of gingival cells to P. gingivalis induces the release of interleukin-6 and tumor necrosis factor-alpha; interleukin-6, in turn, induces CCL2 secretion.

References

30

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

, , +12

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

PubMed · 1997 · 66.5K citations

Correlations and interactions in the production of interleukin-6 (IL- 6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF

R. N. Schindler, Stefan Endres, R Ghorbani et al. · Blood · 1990 · 993 citations · Full text

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

Suzanne M. Hurst, Thomas S. Wilkinson, Rachel M. McLoughlin et al. · Immunity · 2001 · 808 citations · Full text

, , +12

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

Herbert Tilg, Elizabeth Trehu, MB Atkins et al. · Blood · 1994 · 792 citations · Full text