Altered circadian activity rhythms and sleep in mice devoid of prion protein

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

Hansruedi Büeler, Marek Fischer, Yolande Lang et al. · Nature · 1992 · 1.7K citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

Mutagenesis and Mapping of a Mouse Gene, <i>Clock</i> , Essential for Circadian Behavior

Martha Hotz Vitaterna, David P. King, Anne‐Marie Chang et al. · Science · 1994 · 1.6K citations

Life Sciences, Genetics, Molecular Genetics +17

Prion protein is necessary for normal synaptic function

John Collinge, Miles A. Whittington, Katie Sidle et al. · Nature · 1994 · 792 citations

Life Sciences, Molecular Biology, Neuroscience +14

Fatal Familial Insomnia and Dysautonomia with Selective Degeneration of Thalamic Nuclei

E Lugaresi, Rossella Medori, Pasquale Montagna et al. · New England Journal of Medicine · 1986 · 636 citations

Medicine, Neurology, Neuroscience +17

Fatal Familial Insomnia, a Prion Disease with a Mutation at Codon 178 of the Prion Protein Gene

Rossella Medori, Hans-Juergen Tritschler, Andréa LeBlanc et al. · New England Journal of Medicine · 1992 · 607 citations · Full text

Veterinary Medicine, Genetics, Neurology +17