Journal of Pediatric Gastroenterology and Nutrition · 1993 · 22 citations · 0 references
AgricultureNutritionNutritional SciencesChild NutritionNutritional ToxicologyPediatric NutritionChromium NutritionChromium ToxicologyMicronutrient Deficiency In ChildhoodMicronutrient RequirementsMicronutrient ToxicityParenteral NutritionBlood Chromium LevelsChromium DeficiencyChromium KineticsChromium Status AssessmentCorrelationParenteral Nutrition Administration
Chromium (Cr) dosage was assayed in i.v. nutrition, serum, and losses of five children on total parenteral nutrition for > or = 4 weeks. The Cr supply (4.7 +/- 1.2 micrograms/kg/day) was above recommended levels (0.5 microgram/kg/day). Serum (18.2 +/- 1.8 micrograms/L) and urine (37.4 +/- 10.5 micrograms/L) were also higher than control values (0.7-0.9 microgram/L and 0.2-0.8 microgram/L, respectively). Serum and urine Cr concentrations displayed a positive correlation. Serum Cr and Fe showed a negative correlation. These results confirm the potential toxicity of Cr previously reported in animals. Cr levels of i.v. nutrition solutes should be checked thoroughly.