Concepedia

Association of IL23R and ATG16L1 with susceptibility of Crohn’s disease in Chinese population

Jie Zhang, Jiebin Chen, Jianjun Gu, Huimin Guo, Weichang Chen

Scandinavian Journal of Gastroenterology · 2014 · 15 citations · 32 references

Abstract

The original genome-wide association studies finding on ATG16L1 gene should be robust and this gene does play a role in the pathogenesis of CD in the Chinese population. However, the role of IL23R gene in the occurrence of CD remains obscure.

References

32

Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

Mark S. Silverberg, Jack Satsangi, Tariq Ahmad et al. · Canadian Journal of Gastroenterology · 2005 · 3.3K citations · Full text

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

Jochen Hampe, André Franke, Philip Rosenstiel et al. · Nature Genetics · 2006 · 1.9K citations

Genome-wide Association Study, Nonsynonymous Snps, Crohn Disease +9

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

John D. Rioux, Ramnik J. Xavier, Kent D. Taylor et al. · Nature Genetics · 2007 · 1.7K citations · Full text

Genome-wide Association Study, Cell Autophagy, Disease Mechanism +10

A Nonsynonymous SNP in ATG16L1 Predisposes to Ileal Crohn’s Disease and Is Independent of CARD15 and IBD5

Natalie J. Prescott, Sheila Fisher, André Franke et al. · Gastroenterology · 2007 · 296 citations

Atg16l1 Predisposes, Mucosal Immunology, Genetics +10

Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease

Keiko Yamazaki, Masakazu Takazoe, Toshihiro Tanaka et al. · Journal of Human Genetics · 2002 · 293 citations · Full text

Autoimmune Disease, Disease Mechanism, Genetics +11