A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn’s disease☆

Hiroaki Ito, Masakazu Takazoe, Yoshihiro Fukuda, +7

Gastroenterology

InflammationChronic Inflammatory DiseasesAllergyMucosal ImmunologyImmunology +6

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

Keiko Yamazaki, Dermot McGovern, Jiannis Ragoussis, +14

Human Molecular Genetics

Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease

Keiko Yamazaki, Masakazu Takazoe, Toshihiro Tanaka, +2

Journal of Human Genetics

Autoimmune DiseaseDisease MechanismGeneticsPathogenesisImmunology +9

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn’s disease in Japanese patients

Keiko Yamazaki, Yoshihiro Onouchi, Masakazu Takazoe, +3

Journal of Human Genetics

Genome-wide Association StudyAssociation AnalysisGenetic VariantsGeneticsImmunology +6

Free‐breathing diffusion‐weighted imaging for the assessment of inflammatory activity in Crohn's disease

Shigeru Kiryu, Keiichi Dodanuki, Hidemasa Takao, +6

Journal of Magnetic Resonance Imaging

A Genome-Wide Association Study Identifies 2 Susceptibility Loci for Crohn's Disease in a Japanese Population

Keiko Yamazaki, Junji Umeno, Atsushi Takahashi, +21

Gastroenterology

Genome-wide Association StudyDisease SusceptibilityPathogenesisGenetic EpidemiologyPathology +8

Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease

Keiko Yamazaki, Masakazu Takazoe, Torao Tanaka, +6

Journal of Human Genetics

Association AnalysisCrohn DiseaseGenetic EpidemiologyGastroenterologyPathology +5

Adsorptive granulocyte and monocyte apheresis for refractory Crohn?s disease: an open multicenter prospective study

Yoshihiro Fukuda, Toshiyuki Matsui, Yasuo Suzuki, +10

Journal of Gastroenterology

InflammationAdsorptive GranulocyteAutoimmune DiseaseMucosal ImmunologyGranulocyte +9

HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn's Disease

Yukinori Okada, Keiko Yamazaki, Junji Umeno, +12

Gastroenterology

Genetic EpidemiologyImmunologyAutoimmunityReduces RiskHla Typing +6

HLA-linked susceptibility and resistance genes in Crohn's disease

Atsushi Nakajima, Nobuyuki Matsuhashi, Tatsuhiko Kodama, +3

Gastroenterology

HlaAutoimmune DiseaseHuman Leukocyte AntigenMedicinePathogenesis +7