Concepedia

A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

Richard Wooster, Jonathan Mangion, Rosalind A. Eeles, Simon A. Smith, Mitch Dowsett, D. Averill, Peter Barrett‐Lee, Douglas F. Easton, Bruce A.J. Ponder, Michael R. Stratton

Nature Genetics · 1992 · 251 citations · 20 references

Concepts

Life SciencesGeneticsOncologyEndocrine GeneticsHuman GeneticsMedical GeneticsEndocrine Tumor GeneticsGermline Cancer PredispositionGermline Cancer SusceptibilityHereditary Cancer SyndromesInherited Endocrine SyndromesSteroidogenesis GeneticsAndrogen Receptor GeneticsAndrogen ReceptorsDisorders Of Androgen BiosynthesisFamilial Endocrine Tumor SyndromesGermline Cancer Predisposition SyndromesHereditary Endocrine Tumor SyndromesSteroid Hormone Receptor Mutations

References

20

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

David Malkin, Frederick P. Li, Louise C. Strong et al. · Science · 1990 · 3.8K citations

Life Sciences, Genetics, Oncology +17

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

Albert R. La Spada, Elizabeth Wilson, Dennis B. Lubahn et al. · Nature · 1991 · 2.8K citations

Medicine, Genetics, Molecular Genetics +14

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

Jeff Hall, Ming K. Lee, Beth Newman et al. · Science · 1990 · 2.5K citations

Life Sciences, Genetics, Molecular Genetics +14

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

Jerry Pelletier, Wendy Bruening, Clifford E. Kashtan et al. · Cell · 1991 · 954 citations

Medicine, Genetics, Molecular Genetics +17

MEXILETINE FOR TREATMENT OF CHRONIC PAINFUL DIABETIC NEUROPATHY

Anders Dejgård, Palle Petersen, Jens Kastrup · The Lancet · 1988 · 533 citations

Medicine, Pharmacology, Pharmacotherapy +10