Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: Therapeutic efficacy and possible mechanisms of action

Chemically induced mouse models of intestinal inflammation

Stefan Wirtz, Clemens Neufert, Benno Weigmann et al. · Nature Protocols · 2007 · 1.5K citations

Life Sciences, Immunology, Pathobiology +14

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

Life Sciences, Immunology, Pathology +17

Loss of the Tight Junction Protein ZO-1 in Dextran Sulfate Sodium Induced Colitis

Lisa S. Poritz, K.I. Garver, Cecelia Green et al. · Journal of Surgical Research · 2007 · 408 citations

Life Sciences, Cell Biology, Immunology +14

Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

Peter Suenaert, Veerle Bulteel, Liesbeth Lemmens et al. · The American Journal of Gastroenterology · 2002 · 389 citations

Life Sciences, Immunology, Immunoregulation +13

Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease.

S J McKenzie, Mark S. Baker, Gary D. Buffinton et al. · Journal of Clinical Investigation · 1996 · 347 citations · Full text

Life Sciences, Biochemistry, Pathobiology +17