Cancer · 1979 · 223 citations · 13 references
MedicineOncologyRadiation OncologyCutaneous OncologyDermatologic SurgeryOncologic SurgeryCervical Lymph Node MetastasisCutaneous NeoplasmsNeck DissectionNeck PathologyRegional Nodal IrradiationSkin TumorsAngiosarcoma TherapyLymph Node MetastasesPostoperative Nodal IrradiationRegional Lymph Node SpreadSpreadingVascular Skin Tumors
Between 1920 and 1970, 13 patients (7 men and 6 women) with cutaneous angiosarcomas of the head or neck were treated at the Mayo Clinic; the mean age of the patients was 66 years. Three clinical patterns were noted: a superficial spreading type, a nodular type, and an ulcerating type. There were no predisposing benign lesions; however, in one patient, angiosarcoma developed in an area of previously irradiated skin. Three modes of therapy were used: surgery alone, radiation alone, and surgery with postoperative irradiation. Of the 13 patients, 2 survived more than 5 years and 2 were alive within 1 year of therapy. Because cervical lymph node spread is common, lymph node clearance is recommended for patients with lateralized lesion or with palpable lymphadenopathy at presentation.
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Juan Rosaí, Hatton W. Sumner, Major M.C. et al. · Human Pathology · 1976 · 301 citations
Lymphangiosarcoma arising in chronic lymphedematous extremities
Anthony H. Woodward, John C. Ivins, Edward H. Soule · Cancer · 1972 · 272 citations
Treatment of cancer and allied diseases
The American Journal of Surgery · 1940 · 232 citations · Full text
Medicine, Plastic Surgery, Surgery +10