Carbon-13 Nuclear Magnetic Resonance Spectrum of Colchicine

Abstract

Abstract 13C NMR chemical shifts of tropolone, tropolone methyl ether and colchicine are reported. The various carbon resonances have been assigned on the basis of substituent effects on benzene shifts, intensities, multiplicities generated in SFORD spectra and the comparison with structurally related compounds like tropolone and tropolone methyl ether. Key Words: Carbon-13 NMRsingle frequency off-resonance decoupled (SFORD)chemical shiftassignmentstropolonetropolone methyl ethercolchicine