Synthesis and biological testings as inhibitors of HMGCoA reductase of the seco-acid of tuckolide and its C-7 epimer

N-methoxy-n-methylamides as effective acylating agents

Steven Nahm, Steven M. Weinreb · Tetrahedron Letters · 1981 · 1.8K citations

Pharmacy, Medicinal Chemistry, Pharmacology +5

Directed reduction of .beta.-hydroxy ketones employing tetramethylammonium triacetoxyborohydride

David A. Evans, Kevin T. Chapman, Erick M. Carreira · Journal of the American Chemical Society · 1988 · 946 citations

Natural Sciences, Biochemistry, Chemistry +6

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog.

Petri T. Kovanen, D W Bilheimer, J L Goldstein et al. · Proceedings of the National Academy of Sciences · 1981 · 425 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Analysis of two carbon-13 NMR correlations for determining the stereochemistry of 1,3-diol acetonides

Scott D. Rychnovsky, Bruce N. Rogers, Guang Yang · The Journal of Organic Chemistry · 1993 · 341 citations

Natural Sciences, Biochemistry, Chemistry +8

Improved procedure for preparation of optically active 3-hydroxyglutarate monoesters and 3-hydroxy-5-oxoalkanoic acids

Peter D. Theisen, Clayton H. Heathcock · The Journal of Organic Chemistry · 1988 · 119 citations

Natural Sciences, Biochemistry, Chemistry +5