Concepedia

A highly efficient methodology of asymmetric epoxidation based on a novel chiral sulfur ylide

Francisco Sarabia, Samy Chammaa, M. García-Castro, Francisca Martín‐Gálvez

Chemical Communications · 2009 · 45 citations · 13 references

DOI

Concepts

Abstract

A new type of chiral sulfur ylides has been synthesized and their reactivities against carbonyl compounds tested, showing a high degree of stereoselectivity in the formation of trans epoxy amides under very mild reaction conditions.

References

13

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Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization

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Catalytic, Asymmetric Sulfur Ylide-Mediated Epoxidation of Carbonyl Compounds:  Scope, Selectivity, and Applications in Synthesis

Varinder K. Aggarwal, C. L. Winn · Accounts of Chemical Research · 2004 · 513 citations

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The Use of Tosylhydrazone Salts as a Safe Alternative for Handling Diazo Compounds and Their Applications in Organic Synthesis

J. Robin Fulton, Varinder K. Aggarwal, Javier de Vicente · European Journal of Organic Chemistry · 2005 · 395 citations · Full text

, , +12

The complexity of catalysis: origins of enantio- and diastereocontrol in sulfur ylide mediated epoxidation reactions

Varinder K. Aggarwal, Jeffery Richardson · Chemical Communications · 2003 · 145 citations

, , +13