Tolerance to the analgesic effect of buprenorphine, butorphanol, nalbuphine, and cyclorphan, and cross-tolerance to morphine

Opioid analgesics and antagonists

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Medicine, Pharmacology, Pharmacotherapy +12

The Effect of Intrinsic Efficacy on Opioid Tolerance 

Alokesh Duttaroy, Byron C. Yoburn · Anesthesiology · 1995 · 212 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Evaluation of Nalbuphine Hydrochloride

Russell R. Miller · American Journal of Health-System Pharmacy · 1980 · 75 citations

Medicine, Pharmacology, Pharmacotherapy +12

Nalbuphine, a mixed kappa 1 and kappa 3 analgesic in mice.

Chaim G. Pick, Dennis Paúl, Gavril W. Pasternak · Journal of Pharmacology and Experimental Therapeutics · 1992 · 73 citations

Medicine, Pharmacology, Neuropharmacology +15

Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine

Valérie Kayser, Jean‐Marie Besson, G. Guilbaud · European Journal of Pharmacology · 1991 · 69 citations

Medicine, Pharmacology, Pharmacotherapy +16