Facile removal of new base protecting groups useful in oligonucleotide synthesis

Polymer support oligonucleotide synthesis XVIII^1.2): use of<i>β</i>-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

N. D. SINHA, J. Biernat, J. F. A. McManus et al. · Nucleic Acids Research · 1984 · 848 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

<b>Studies on Polynucleotides. XXIV.</b>¹ <b>The Stepwise Synthesis of Specific Deoxyribopolynucleotides (4).</b>² <b>Protected Derivatives of Deoxyribonucleosides and New Syntheses of Deoxyribonucleoside-3″ Phosphates</b>³

Heinz Schaller, G. Weimann, B. Lerch et al. · Journal of the American Chemical Society · 1963 · 402 citations

Pharmacy, Biochemistry, Enzymology +7

CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40

Hans Weber, H. G. Khorana · Journal of Molecular Biology · 1972 · 174 citations

Life Sciences, Genetics, Molecular Biology +8

New effective method for the synthesis of oligonucleotides via phosphotriester intermediates

V. A. Efimov, Sergey Reverdatto, O. G. Chakhmakhcheva · Nucleic Acids Research · 1982 · 114 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +14

CV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50

H. Büchi, H. G. Khorana · Journal of Molecular Biology · 1972 · 77 citations

Life Sciences, Biochemistry, Molecular Biology +10