Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

George Scatchard · Annals of the New York Academy of Sciences · 1949 · 19.9K citations

Natural Sciences, Biophysics, Chemistry +9

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Medicine, Biostatistics, Pharmacology +17

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

June L. Biedler, Lawrence Helson, Barbara A. Spengler · PubMed · 1973 · 1.3K citations

Medicine, Cell Biology, Oncology +16

Pirenzepine distinguishes between different subclasses of muscarinic receptors

Rudolf Hammer, Christopher P. Berrie, N.J.M. Birdsall et al. · Nature · 1980 · 1.3K citations

Medicine, Neuroscience, Pharmacology +16