Influence of endothelium and nitrovasodilators on free thiols and disulfides in porcine coronary smooth muscle

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

Richard Palmer, Anthony G. Ferrige, Salvador Moncada · Nature · 1987 · 10.8K citations

Veterinary Medicine, Cell Biology, Physiology +10

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

L J Ignarro, Georgette M. Buga, K S Wood et al. · Proceedings of the National Academy of Sciences · 1987 · 5.1K citations · Full text

Medicine, Pharmacology, Physiology +12

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Life Sciences, Biophysics, Physiology +6

Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide

Paul R. Myers, Robert L. Minor, Ricardo Guerra et al. · Nature · 1990 · 982 citations

Life Sciences, Pharmacology, Physiology +5

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

Martin Feelisch, E. Noack · European Journal of Pharmacology · 1987 · 897 citations

Life Sciences, Biochemistry, Molecular Biology +7