Concepedia

Which is the primary etiologic event in Otsuka Long-Evans Tokushima Fatty rats, a model of spontaneous non—insulin-dependent diabetes mellitus, insulin resistance, or impaired insulin secretion?

Kaori Ishida, Akira Mizuno, Min Zhu, Toshiaki Sano, Kenji Shima

Metabolism · 1995 · 89 citations · 16 references

DOI

Concepts

References

16

THE GLUCOSE FATTY-ACID CYCLE ITS ROLE IN INSULIN SENSITIVITY AND THE METABOLIC DISTURBANCES OF DIABETES MELLITUS

P J Randle, P. B. Garland, C. N. Hales et al. · The Lancet · 1963 · 5.2K citations

, , +10

"Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes.

Per Björntorp · Arteriosclerosis An Official Journal of the American Heart Association Inc · 1990 · 1.1K citations · Full text

, , +14

Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain

K Kawano, Tsukasa Hirashima, Seijiro Mori et al. · Diabetes · 1992 · 875 citations

, , +17

Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats.

Luciano Rossetti, Douglas J. Smith, Gerald I. Shulman et al. · Journal of Clinical Investigation · 1987 · 808 citations · Full text

, , +16

Insulin and Obesity in the Zucker Genetically Obese Rat “Fatty”

Lois M. Zucker, Harry N. Antoniades · Endocrinology · 1972 · 420 citations

, , +17