Systemic administration of endorphins selectively alters open field behavior of rats

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

W R Martin, C. G. Eades, JP Thompson et al. · Journal of Pharmacology and Experimental Therapeutics · 1976 · 3K citations

Medicine, Pharmacology, Veterinary Pharmacology +16

Endogenous opioid peptides: multiple agonists and receptors

John A.H. Lord, Angela A. Waterfield, John Hughes et al. · Nature · 1977 · 2.5K citations

Medicine, Pharmacology, Neuroendocrinology +9

Opiates and endogenous opioid peptides

John Kelly, Raymond Dingledine · Trends in Biochemical Sciences · 1977 · 1.3K citations

Medicine, Neuroscience, Pharmacology +12

Common precursor to corticotropins and endorphins

Richard E. Mains, Betty Eipper, Nicholas Ling · Proceedings of the National Academy of Sciences · 1977 · 1.1K citations · Full text

Life Sciences, Biochemistry, Endocrinology +17