Inheritance of Avoidance Conditioning in Mice: A Diallel Study

Abstract

Significant genetic differences were demonstrated in the rate of avoidance conditioning among offspring from all 25 mating combinations of 5 highly inbred mouse strains. Hybrids of C3H parents learned fastest, while those of A/JAX parents learned slowest. Most hybrids learned better than either parent. Evidence that differential influences of the early maternal environment affected the rate of learning was not supported.