Concepedia

Regulation of osteoclastogenesis through Tim-3: possible involvement of the Tim-3/galectin-9 system in the modulation of inflammatory bone destruction

Kanako Moriyama, Akiko Kukita, Yin-Ji Li, Norihisa Uehara, Jing-Qi Zhang, Ichiro Takahashi, Toshio Kukita

Laboratory Investigation · 2014 · 33 citations · 23 references

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23

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature · 2002 · 1.6K citations

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Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

Shigeki Chiba, Muhammad Baghdadi, Hisaya Akiba et al. · Nature Immunology · 2012 · 827 citations · Full text

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Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

Masako Seki, Souichi Oomizu, Ken-mei Sakata et al. · Clinical Immunology · 2008 · 466 citations

, , +14

RANKL-induced DC-STAMP Is Essential for Osteoclastogenesis

Toshio Kukita, Naohisa Wada, Akiko Kukita et al. · The Journal of Experimental Medicine · 2004 · 361 citations · Full text

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Identification and Characterization of Galectin-9, a Novel β-Galactoside-binding Mammalian Lectin

Jun Wada, Yashpal S. Kanwar · Journal of Biological Chemistry · 1997 · 335 citations · Full text

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