Concepedia

1,4,7-Triazacyclononane-1-succinic acid-4,7-diacetic acid (NODASA): a new bifunctional chelator for radio gallium-labelling of biomolecules

João Paulo André, Helmut R. Maëcke, João Paulo André, Margareta Zehnder, Ludwig Macko, Kayhan G. Akyel

Chemical Communications · 1998 · 83 citations · 7 references

DOI

Concepts

Abstract

A new bifunctional chelator NODASA (1,4,7-triazacyclononane-1-succinic acid-4,7-diacetic acid) has been synthesised, its kinetically inert gallium(III) complex was crystallographically characterized and conjugated to a model aminoacidamide showing the feasibility of a prelabelling approach with 68,67Ga.

References

7

1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive

Louis A. Carpino · Journal of the American Chemical Society · 1993 · 1.5K citations

, , +14

DOTATOC: A powerful new tool for receptor-mediated radionuclide therapy

Andreas Otte, E. Jermann, Martin Béhé et al. · European Journal of Nuclear Medicine and Molecular Imaging · 1997 · 214 citations

, , +9

1,4,7-Triazacyclononane-N,N',N''-triacetate (TCTA), a new hexadentate ligand for divalent and trivalent metal ions. Crystal structures of [CrIII(TCTA)], [FeIII(TCTA)], and Na[CuII(TCTA)].bul.2NaBr.bul.8H2O

Karl Wieghardt, Ursula Bossek, Phalguni Chaudhuri et al. · Inorganic Chemistry · 1982 · 148 citations

, , +12

Stabilities of the Fe(III), Ga(III) and In(III) chelates of N,N′,N″-triazacyclononanetriacetic acid

Eric T. Clarke, Arthur E. Martell · Inorganica Chimica Acta · 1991 · 143 citations

, , +5

A novel hexachelating amino-thiol ligand and its complex with gallium(III)

Dennis A. Moore, Phillip E. Fanwick, Michael J. Welch · Inorganic Chemistry · 1990 · 107 citations

, , +15