A concise route to phytosphingosine from lyxose

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

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Life Sciences, Cell Biology, Immunology +16

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

Katsuichi Miyamoto, Sachiko Miyake, Takashi Yamamura · Nature · 2001 · 870 citations

Life Sciences, Immunology, Neurology +15

Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus

Takenori Natori, Masahiro Morita, Kohji Akimoto et al. · Tetrahedron · 1994 · 396 citations

Natural Sciences, Immunology, Marine Biology +11

Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds

Alfred H. Merrill, Sanjay Nimkar, David S. Menaldino et al. · Biochemistry · 1989 · 250 citations

Life Sciences, Biochemistry, Pharmacology +11

Stereochemistry associated with the addition of 2-(trimethylsilyl)thiazole to differentially protected .alpha.-amino aldehydes. Applications toward the synthesis of amino sugars and sphingosines

Alessandro Dondoni, Giancarlo Fantin, Marco Fogagnolo et al. · The Journal of Organic Chemistry · 1990 · 130 citations

Natural Sciences, Biochemistry, Chemistry +12