Concepedia

Activation of the p53–p21Cip1 pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes

Lene Wierød, Carola M. Rosseland, Birgitte Lindeman, Morten P. Oksvold, H. Grøsvik, Ellen Skarpen, Henrik S. Huitfeldt

Oncogene · 2007 · 20 citations · 45 references

DOI

Concepts

References

45

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

, , +12

New functional activities for the p21 family of CDK inhibitors.

Joshua LaBaer, Michelle D. Garrett, Lauren Stevenson et al. · Genes & Development · 1997 · 1.4K citations · Full text

, , +14

mdm2 expression is induced by wild type p53 activity.

Yaacov Barak, T. Juven, Rebecca Haffner et al. · The EMBO Journal · 1993 · 1.3K citations · Full text

, , +8