Glutathione-s-transferase pi expression in leukaemia: a comparative analysis with mdr-1 data

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

Medicine, Cell Biology, Pharmacology +11

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

Chang-jie Chen, Janice E. Chin, Kazumitsu Ueda et al. · Cell · 1986 · 1.9K citations

Life Sciences, Genetics, Molecular Biology +14

Expression of Multidrug Resistance Gene in Human Cancers

Lori J. Goldstein, Hanan Galski, Antonio Tito Fojo et al. · JNCI Journal of the National Cancer Institute · 1989 · 1.3K citations

Medicine, Cancer Biology, Oncology +11

Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.

Bengt Mannervik, Per Ålin, Claes Guthenberg et al. · Proceedings of the National Academy of Sciences · 1985 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

Norbert Kartner, Deanna Evernden-Porelle, Grace Bradley et al. · Nature · 1985 · 922 citations

Pharmacy, Molecular Biology, Pharmacology +11