Concepedia

Synthesis and resolution of β-(aminomethyl)-4-chlorobenzeneethanesulfinic acid a potent gabaB receptor ligand

Nicholas I. Carruthers, James M. Spitler, Shing-Chun Wong, David J. Blythin, Ho‐Jane Shue, Stanley Mittelman

Bioorganic & Medicinal Chemistry Letters · 1995 · 18 citations · 9 references

DOI

Concepts

References

9

(–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor

Norman G. Bowery, David R. Hill, Alan L. Hudson et al. · Nature · 1980 · 1.1K citations

, , +16

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

David R. Hill, Norman G. Bowery · Nature · 1981 · 1K citations

, , +16

Phaclofen: a peripheral and central baclofen antagonist

David I.B. Kerr, Jennifer Ong, Rolf H. Prager et al. · Brain Research · 1987 · 349 citations

, , +4

Prevention of the agonist binding to gamma-aminobutyric acid B receptors by guanine nucleotides and islet-activating protein, pertussis toxin, in bovine cerebral cortex. Possible coupling of the toxin-sensitive GTP-binding proteins to receptors.

Taku Asano, M Ui, Naotaka Ogasawara · Journal of Biological Chemistry · 1985 · 147 citations · Full text

, , +17

Antagonism at GABAB receptors by saclofen and related sulphonic analogues of baclofen and GABA

David I.B. Kerr, Jennifer Ong, Graham A.R. Johnston et al. · Neuroscience Letters · 1989 · 54 citations

, , +14