Concepedia

Decreased mitochondrial bioenergetics and calcium buffering capacity in the basal ganglia correlates with motor deficits in a nonhuman primate model of aging

Jignesh D. Pandya, Richard Grondin, Heather M. Yonutas, Hamed Haghnazar, Don M. Gash, Zhiming Zhang, Patrick G. Sullivan

Neurobiology of Aging · 2015 · 69 citations · 76 references

DOI

Concepts

References

76

Aging: A Theory Based on Free Radical and Radiation Chemistry

Denham Harman · Journal of Gerontology · 1956 · 8.5K citations

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The Biologic Clock: The Mitochondria?

Denham Harman · Journal of the American Geriatrics Society · 1972 · 2K citations

, , +17

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

Andreas Bender, Kim J. Krishnan, Christopher M. Morris et al. · Nature Genetics · 2006 · 1.6K citations

, , +17

Mitochondrial Genetics: A Paradigm for Aging and Degenerative Diseases?

Douglas C. Wallace · Science · 1992 · 1.3K citations

, , +17

‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease

C. Savio Chan, Jaime N. Guzmán, Ema Ilijić et al. · Nature · 2007 · 906 citations

, , +16