Concepedia

Blockade of HERG channels by HIV protease inhibitors

Blake D. Anson, Joel Weaver, Michael J. Ackerman, Omobosola Akinsete, Keith Henry, Craig T. January, Andrew D. Badley

The Lancet · 2005 · 157 citations · 4 references

Concepts

MedicineMolecular BiologyPharmacologyCell SignalingIon Channel BiophysicsMolecular PharmacologyAntiretroviral TherapyAntiviral AgentsEnzyme InhibitionIon Channel PharmacologyIon Channel RegulationIon ChannelsChannelsIon Channel TargetingMechanism Of Ion Channel BlockadeProtease InhibitorsViral Protease Inhibition

References

4

Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

Frank J. Palella, Kathleen M. Delaney, Anne C. Moorman et al. · New England Journal of Medicine · 1998 · 9.5K citations

Public Health, Infectious Disease Control, Infectious Diseases +15

Beta-adrenergic receptor subtype-specific signaling in cardiac myocytes from beta(1) and beta(2) adrenoceptor knockout mice.

Eric Devic, Yang K. Xiang, Dianna J. Gould et al. · PubMed · 2001 · 205 citations

Life Sciences, Cardiology, Physiology +17

Molecular and functional characterization of common polymorphisms in HERG (KCNH2) potassium channels

Blake D. Anson, Michael J. Ackerman, David J. Tester et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2004 · 130 citations

Life Sciences, Genetics, Molecular Genetics +17

Efavirenz-Associated QT Prolongation and Torsade de Pointes Arrhythmia

Ricardo Castillo, Ronald P. Pedalino, Nabil El‐Sherif et al. · Annals of Pharmacotherapy · 2002 · 58 citations

Medicine, Cardiology, Pharmacology +17