Concepedia

Mutations at Arginine 352 Alter the Pore Architecture of CFTR

Guiying Cui, Andrew R. W. O’Brien, Bin‐Lin Song, Nael A. McCarty

The Journal of Membrane Biology · 2008 · 54 citations · 58 references

Open access

Concepts

Life SciencesBiochemistryMolecular BiologyMolecular BiophysicsStructural BiologyChannel StructureCystic FibrosisProtein StructureCftr Gene MutationsCftr Protein FunctionPore ArchitecturePore Network ArchitecturePorin Proteins

References

58

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng, Richard J. Gregory, John Marshall et al. · Cell · 1990 · 1.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

The human ATP-binding cassette (ABC) transporter superfamily

Michael Dean, Yannick Hamon, Giovanna Chimini · Journal of Lipid Research · 2001 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson, Richard J. Gregory, Simon Thompson et al. · Science · 1991 · 1.1K citations

Natural Sciences, Cell Biology, Molecular Biology +17

Electrostatic Effects in Proteins

M. F. Perutz · Science · 1978 · 746 citations

Life Sciences, Biochemistry, Biophysics +17