Public Health · 1995 · 21 citations · 13 references
Public HealthChild HealthPediatricsHuman NutritionMicronutrient DeficiencyPediatric EpidemiologyMicronutrient Deficiency In ChildhoodVitamin A DeficiencyChildhood Vitamin A DeficiencyClinical Signs DetectionCross-sectional Prevalence SurveysPositive Clinical SignsVitamin A Deficiency EpidemiologyVitamin Deficiencies
UNLABELLED: Vitamin A deficiency is a major cause of morbidity, mortality and blindness among children. Although vitamin A deficiency is known to affect many children in developing countries, the magnitude of the problem in the South Pacific region is unclear. METHODS: Five cross-sectional surveys for vitamin A deficiency were conducted between 1989 and 1992 in the Republic of Kiribati, Tuvalu, the Republic of Vanuatu, Solomon Islands and the Cook Islands. RESULTS: In total, 10,673 children between the ages of 6 and 72 months were examined for clinical signs of vitamin A deficiency (nightblindness and xerophthalmia). The prevalence of xerophthalmia was 14.76% in the Republic of Kiribati, 1.55% in Solomon Islands, 0.59% in the Cook Islands, 0.28% in Tuvalu, and 0.11% in Vanuatu. The most common clinical findings were Bitot's spots followed by nightblindness. Xerophthalmia were more common among boys (Kiribati P < 0.001, Solomon Islands P = 0.03) and tended to occur in older preschool children (P < 0.0001). CONCLUSIONS: These studies suggest that vitamin A deficiency is a public health problem in the Republic of Kiribati and Solomon Islands.
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IMPACT OF VITAMIN A SUPPLEMENTATION ON CHILDHOOD MORTALITY
Alfred Sommer, Edi Djunaedi, A.A Loeden et al. · The Lancet · 1986 · 685 citations
INCREASED MORTALITY IN CHILDREN WITH MILD VITAMIN A DEFICIENCY
Alfred Sommer, G Hussaini, Ignatius Tarwotjo et al. · The Lancet · 1983 · 458 citations
REDUCTION OF STRESS/ CATECHOLAMINE-INDUCED CARDIAC NECROSIS BY BETA1-SELECTIVE BLOCKADE
JohnM. Cruickshank, Jean-P. Degaute, T. Kuurne et al. · The Lancet · 1987 · 455 citations