Genetic predictors of medically refractory ulcerative colitis

Talin Haritunians, Kent D. Taylor, Stephan R. Targan, Marla C. Dubinsky, Andrew Ippoliti, Soonil Kwon, Xiuqing Guo, Gil Melmed, Dror Berel, Emebet Mengesha,

Inflammatory Bowel Diseases · 2010 · 148 citations · 62 references

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Abstract

A SNP-based risk scoring system, identified here by GWAS analyses, may provide a useful adjunct to clinical parameters for predicting the natural history of UC. Furthermore, discovery of genetic processes underlying disease severity may help to identify pathways for novel therapeutic intervention in severe UC.

References

62