Concepedia

Use of antisense oligonucleotides targeting the antiapoptotic gene, clusterin/testosterone-repressed prostate message 2, to enhance androgen sensitivity and chemosensitivity in prostate cancer

M.E. Gleave, Hideaki Miyake, Toby Zellweger, Kim Chi, Laura July, Colleen Nelson, Paul S. Rennie

Urology · 2001 · 78 citations · 63 references

DOI

Concepts

References

63

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Lawrence Boise, Maribel González‐García, C E Postema et al. · Cell · 1993 · 3.1K citations · Full text

, , +12

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.

Timothy J. McDonnell, Patricia Troncoso, Shawn Brisbay et al. · PubMed · 1992 · 1.1K citations

, , +17

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase

Noah Craft, Yuriy Shostak, Michael Carey et al. · Nature Medicine · 1999 · 984 citations

, , +15

Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

Marc Colombel, Fraser Symmans, Sixtina Gil et al. · PubMed · 1993 · 595 citations

, , +14

Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo.

Anthony J. Raffo, Harris Perlman, Min‐Wei Chen et al. · PubMed · 1995 · 551 citations

, , +15