A mutant l-asparaginase II signal peptide improves the secretion of recombinant cyclodextrin glucanotransferase and the viability of Escherichia coli

SecA interacts with secretory proteins by recognizing the positive charge at the amino terminus of the signal peptide in Escherichia coli.

Mitsuru Akita, Shin Sasaki, S. Matsuyama et al. · Journal of Biological Chemistry · 1990 · 227 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Polymeric sequences reveal a functional interrelationship between hydrophobicity and length of signal peptides.

Margaret M. Chou, Debra A. Kendall · Journal of Biological Chemistry · 1990 · 96 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Extracellular recombinant protein production from an <i>Escherichia coli lpp</i> deletion mutant

Hyun‐Dong Shin, Rachel R. Chen · Biotechnology and Bioengineering · 2008 · 86 citations

Life Sciences, Biotechnology, Microbiology +16

Growth rate-dependent changes in Escherichia coli membrane structure and protein leakage

Applied Microbiology and Biotechnology · 2002 · 74 citations

Life Sciences, Biochemistry, Microbiology +16

Positively charged lysine at the N‐terminus of the signal peptide of the <i>Escherichia coli</i> alkaline phosphatase provides the secretion efficiency and is involved in the interaction with anionic phospholipids

M. A. Nesmeyanova, A. L. Karamyshev, Zemphyra N Karamysheva et al. · FEBS Letters · 1997 · 68 citations · Full text

Life Sciences, Biochemistry, Microbiology +16