Epigenetic Silencing of MicroRNA-375 Regulates PDK1 Expression in Esophageal Cancer

Combinatorial microRNA target predictions

Azra Krek, Dominic Grün, Matthew N. Poy et al. · Nature Genetics · 2005 · 4.6K citations

Systems Biology, Functional Genomics, Genetics +6

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

Yannick Ladeiro, Gabrielle Couchy, Charles Balabaud et al. · Hepatology · 2008 · 676 citations · Full text

miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma

Mayuko Furuta, Ken-ich Kozaki, Shinji Tanaka et al. · Carcinogenesis · 2009 · 573 citations · Full text

Mature Mirna Genes, Pathology, Epigenetics +20

miR-375 Targets 3′-Phosphoinositide–Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic β-Cells

Abdelfattah El Ouaamari, Nadine Baroukh, Geert A. Martens et al. · Diabetes · 2008 · 423 citations · Full text

MicroRNA-375 Is Downregulated in Gastric Carcinomas and Regulates Cell Survival by Targeting PDK1 and 14-3-3ζ

Yoshiyuki Tsukamoto, Chisato Nakada, Tsuyoshi Noguchi et al. · Cancer Research · 2010 · 391 citations

Pathology, Cell Death, Cancer Biology +17