Ulceroprotective activity of the flavonoids of <i>Genista rumelica</i> Vel

Abstract

Abstract Ulceroprotective action of several flavonoid compounds isolated from Genista rumelica Vel. (total flavonoid mixture, luteoline‐7‐glycoside, genistine) was established on five models of gastric ulcer in rats, genistine being the most active. Comparison was made against several standard antiulcer durgs (Succus Liquiritiae, Caved S, Almagel). A combined drug Flavogastrol, containing total flavonoid mixture, Semmen Lini gel and antacid compounds, was prepared and demonstrated ulceroprotective activity and low toxicity.