Concepedia

Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin

Pornngarm Limtrakul, Wanida Chearwae, Suneet Shukla, Chada Phisalphong, Suresh V. Ambudkar

Molecular and Cellular Biochemistry · 2006 · 207 citations · 33 references

DOI

Concepts

References

33

Anticancer potential of curcumin: preclinical and clinical studies.

Bharat B. Aggarwal, Anushree Kumar, Alok C. Bharti · PubMed · 2003 · 2.6K citations

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Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

Takashi Tsuruo, Harumi Iida, Shigeru Tsukagoshi et al. · PubMed · 1981 · 1.5K citations

, , +7

Biotransformation of Curcumin Through Reduction and Glucuronidation in Mice

Min‐Hsiung Pan, Tsang‐Miao Huang, Jen‐Kun Lin · Drug Metabolism and Disposition · 1999 · 943 citations

, , +8

Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.

Christopher R. Ireson, S Orr, Donald J. L. Jones et al. · PubMed · 2001 · 592 citations

, , +13

Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.

Christopher R. Ireson, Donald J. L. Jones, Samantha Orr et al. · PubMed · 2002 · 562 citations

, , +12