Progesterone receptor-mediated effects of neuroactive steroids

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Firefly luciferase gene: structure and expression in mammalian cells.

Jeffrey R. de Wet, Keith V. Wood, M. DeLuca et al. · Molecular and Cellular Biology · 1987 · 3.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

Maria Dorota Majewska, Neil L. Harrison, Rochelle D. Schwartz et al. · Science · 1986 · 2.2K citations

Medicine, Neuroscience, Pharmacology +17

Identification of a receptor for the morphogen retinoic acid

Vincent Giguère, Estelita S. Ong, Prudimar Segui et al. · Nature · 1987 · 2K citations

Life Sciences, Cell Biology, Molecular Biology +12