Concepedia

Influence of acetylsalicylate on plasma lysophosphatidic acid level in patients with ischemic cerebral vascular diseases

Zhenguang Li, Zhan-cai Yu, Dao-zhen Wang, Weiping Ju, Xia Zhan, Qizhuan Wu, Xijuan Wu, Hai‐Ming Cong, Hong-Hao Man

Neurological Research · 2008 · 38 citations · 13 references

DOI

Abstract

Our findings support a close association between increased plasma LPA level and platelet activation. Acetylsalicylate could decrease plasma LPA levels, which may be used as a mechanism for acetylsalicylate in the prevention of ischemic stroke.

References

13

COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

Robert Altman, L Carreras, Rubén Sierra Díaz et al. · Oxford University Research Archive (ORA) (University of Oxford) · 1994 · 3.3K citations

, , +9

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

BMJ · 1994 · 3.1K citations

Aspirin-Resistant Thromboxane Biosynthesis and the Risk of Myocardial Infarction, Stroke, or Cardiovascular Death in Patients at High Risk for Cardiovascular Events

John W. Eikelboom, Jack Hirsh, Jeffrey I. Weitz et al. · Circulation · 2002 · 1K citations · Full text

The bioactive phospholipid lysophosphatidic acid is released from activated platelets

Thomas Eichholtz, Kees Jalink, Iris Fahrenfort et al. · Biochemical Journal · 1993 · 654 citations

, , +20

Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways

Junken Aoki, Akitsu Taira, Yasukazu Takanezawa et al. · Journal of Biological Chemistry · 2002 · 427 citations · Full text